Intestinal α-Glucosidase Inhibitors in Achillea millefolium
نویسندگان
چکیده
منابع مشابه
Occurence of Phomopsis Sp. on Achillea Millefolium
Throughout many years of studying mycopopulation of weeds, we have found fungi of the Diaporthe/ Phomopsis complex interesting to research. After years of examining plants of Achillea millefolium L., some of them exhibited symptoms of infection typical for Diaporthe/Phomopsis species. A. millefolium was usually found in uncultivated, pasture and forest flora, but also in or nearby sunflower fie...
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Nowadays, medicinal plants used in folk medicine are being increasingly studied and used on pharmaceutical, food and nutraceutical fields. Yarrow (Achillea millefolium L.) is widely used in both folk and official medicine. Therefore, in the present paper different extracts of yarrow inflorescences and upper leaves were investigated for their total polyphenolic content and antioxidant activity u...
متن کاملα-Glucosidase Inhibitors from Vauquelinia corymbosa.
The α-glucosidase inhibitory activity of an aqueous extract and compounds from the aerial parts of V. corymbosa was demonstrated with yeast and rat small intestinal α-glucosidases. The aqueous extract inhibited yeast α-glucosidase with a half maximal inhibitory concentration (IC50) of 28.6 μg/mL. Bioassay-guided fractionation of the extract led to the isolation of several compounds, including o...
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Post-prandial hyperglycemia still remains a problem in the management of type 2 diabetes mellitus. Of all available anti-diabetic drugs, α-glucosidase inhibitors seem to be the most effective in reducing post-prandial hyperglycemia. We conducted a review analyzing the clinical efficacy and safety of α-glucosidase inhibitors, both alone and in combination with other anti-diabetic drugs, with res...
متن کاملPhenolic compounds from Achillea millefolium L. and their bioactivity.
Since antiquity, Achillea millefolium L. (Asteraceae) has been used in traditional medicine of several cultures, from Europe to Asia. Its richness in bioactive compounds contributes to a wide range of medicinal properties. In this study, we assessed A. millefolium methanolic extract and its isolated components for free radical scavenging activity against 2,2-diphenyl-pycrilhydrazyl, total antio...
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ژورنال
عنوان ژورنال: Natural Product Communications
سال: 2017
ISSN: 1934-578X,1555-9475
DOI: 10.1177/1934578x1701200828